Restoring Tamoxifen Sensitivity in Breast Cancer: The Role of lncRNA MALAT1 and NanoCurcumin as Modulators of Drug Resistance.

Biomed Res Int · 2025 · PMC12407302 · PMID 41031251

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did not reach statistical significanceno p-value reported

While reductions in other oncogenic lncRNAs, including UCA1, CYTOR, and HOTAIR, did not reach statistical significance, their downward trends, coupled with the upward trend of the tumor suppressor lncRNA GAS5, further reinforce the hypothesis that NanoCurcumin exerts a global effect on the lncRNA regulatory landscape [ 14 ].

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