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Exercise interventions and serum IGF-1 levels in older adults with frailty and/or sarcopenia: a systematic review and meta analysis.

Front Public Health · 2025 · PMC12408309 · PMID 40917423

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Through subgroup analysis of different exercise intervention types, this study found that the combined training of aerobic and resistance training had a relatively better effect on improving serum IGF-1 concentration in older adult patients with frailty and/or sarcopenia, followed by resistance training alone, while the improvement effect of aerobic training did not reach statistical significance.

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