Association between autologous formalin-fixed tumor vaccine (AFTV) therapy, molecular pathological markers, and survival outcomes in glioblastoma.

Brain Tumor Pathol · 2025 · PMC12408717 · PMID 40773050

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a favorable trendp = 0.07so close (0.05 < p ≤ 0.1)

p53 expression and AFTV efficacy AFTV therapy showed significantly greater efficacy in p53-negative cases, particularly with respect to overall survival ( p = 0.03), while progression-free survival showed a favorable trend ( p = 0.07).

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showed a trendno p-value reported

The distribution of immune cells in PD-L1-positive tumors showed a trend toward increased CD4-positive cells but did not differ significantly from that in PD-L1-negative tumors.

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