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An iPSC-derived neuronal model reveals manganese's role in neuronal endocytosis, calcium flux and mitochondrial bioenergetics.

iScience · 2025 · PMC12410566 · PMID 40917882

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For patient lines, while an increase in P-JNK levels was observed after Mn exposure, it did not reach statistical significance; it is possible that this more modest increase is related to the pre-existing activation of JNK/SAPK in basal conditions.

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