Reduced circulating regulatory T cells in primary Sjögren's syndrome: the contribution of enhanced apoptosis and impaired survival.

Front Immunol · 2025 · PMC12411454 · PMID 40918139

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did not reach statistical significanceno p-value reported

Interestingly, although the downregulation of the PI3K/AKT signaling pathway did not reach statistical significance, this vital pro-survival axis may still contribute to Treg impairment in pSS.

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