AK112 significantly improved PFS in the overall population (HR = 0.51, 95% CI 0.384–0.69) and showed a trend toward improved PFS in patients with BM (HR = 0.55, 95% CI 0.28–1.05) compared to pembrolizumab.
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Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions.
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