Analyzing Npc1 nmf164 mice at P7, we found that although Iba1 mRNA expression was slightly higher in wild-type PAM than in Npc1 nmf164 PAM at P7, the difference did not reach statistical significance ( Fig 4B and D ).
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Role of mTORC1 signaling in postnatal microglia activation preceding neurodegeneration in a mouse model for Niemann-Pick disease Type C.
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