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Preoperative intensity-modulated radiation therapy in lower extremity soft tissue sarcomas with and without dose avoidance of uninvolved skin/subcutaneous tissue.

Cancer · 2025 · PMC12413022 · PMID 40911570

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The preoperative flap‐sparing IG‐IMRT procedure resulted in a 30.5% MWC rate and reduced late toxicities, both of which were numerically lower than in the NCIC‐SR2 trial but did not reach statistical significance.

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