Barely Significant
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Profiling autoantibodies at baseline and during immune checkpoint inhibitor therapy of renal cell carcinoma patients-exploratory results from TITAN-RCC.

ESMO Open · 2025 · PMC12414892 · PMID 40882246

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showed a trendno p-value reported
reported that melanoma patients who developed autoantibodies showed a trend for better survival, whereas a link between irAE occurrence and clinical outcome was not observed. 38 In our prospective study as part of the TITAN-RCC trial, 33 we did not observe a significant association between pre-existing autoantibodies and achieved disease control.

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