Serum S100A12 in the clinical diagnosis of sepsis-induced myocardial dysfunction: an integrated bioinformatics and clinical data analysis.

At protein level, serum S100A12 protein concentration was highest in the SIMD group (19.60 ± 3.36 ng/ml), followed by the non-SIMD group (14.79 ± 2.92 ng/ml), and lowest in the control group (10.33 ± 1.97 ng/ml), with highly significant differences between groups (all p < 0.001) ( Figure 2B ).

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In contrast, lactate, SOFA score, cTnI, and CK-MB did not reach statistical significance in the multivariate model ( p > 0.05 for all).

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