Characterization of neurodegenerative pathologies in adult and pediatric subjects with Down syndrome.

J Alzheimers Dis · 2025 · PMC12417618 · PMID 40785271

Europe PMC DOI

hedged sentence

0.2200

closest p · 4.4× alpha

0.2200

boldest claim

The sentences

did not reach statistical significancep = 0.220not close (p > 0.1)

34 These APOE4 carriers had a slightly lower mean age at death (56.6 years) compared to non-carriers (n = 47, mean age = 58.5 years), although this difference did not reach statistical significance (z score = −1.225, p = 0.220).

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