Germline analysis of an international cohort of pediatric diffuse midline glioma patients.

Neuro Oncol · 2025 · PMC12417819 · PMID 40072012

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significanceP = .059so close (0.05 < p ≤ 0.1)

Tumors with germline deleterious variants in HR-related genes also had a higher median proportion of genome-wide LOH, although this trend did not reach statistical significance ( P = .059).

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