25 , 26 , 27 , 28 Across observational studies, AVR was associated with significantly lower rates of all-cause and cardiovascular mortality compared with CS, whereas these findings trended in favor of AVR across RCTs, but did not reach statistical significance.
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Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis.
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