Functional variants of CFAP410 affect the DNA damage response leading to motor neuron degeneration - Implications for ALS.

iScience · 2025 · PMC12419110 · PMID 40933646

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In contrast, the heterozygous Cfap410 WT/V20M-HA and Cfap410 WT/R73P-HA cell lines showed a trend of reduced cell density at comparable time points ( Figure 3 A), as do the homozygous Cfap410 V20M-HA/V20M-HA and Cfap410 R73P-HA/R73P-HA lines.

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