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Altered Relaxation and Mitochondria-Endoplasmic Reticulum Contacts Precede Major (Mal)Adaptations in Aging Skeletal Muscle and Are Prevented by Exercise.

Aging Cell · 2025 · PMC12419855 · PMID 40586781

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Even though relative GSH:GSSG ratios did not reach statistical significance across groups, eAMD muscles had a ~ 50% lower ratio than the other groups, suggesting a potential increase in oxidant load (Figure S4B–D ).

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