Allele-specific HLA LOH in solid tumors: distinct patterns by tumor type and potential prognostic relevance.

J Immunother Cancer · 2025 · PMC12421593 · PMID 40930743

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showed a trendno p-value reported

For instance, A*02:01 -specific LOH was linked to worse survival in CRC (HR 0.5355, 95% CI 0.2991 to 0.9589, p=0.0094) but showed a trend toward improved survival in NSCLC (HR 1.249, 95% CI 0.7778 to 2.005).

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