Barely Significant
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Randomized phase 2a trial assessing a novel septin molecular glue in Alzheimer's disease.

Alzheimers Dement · 2025 · PMC12426855 · PMID 40937833

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nominally significantno p-value reported
In the verum group, a nominally significant change from baseline was observed for peptides representing A4, a non‐amyloidogenic amyloid precursor protein (APP) processing product, chromogranin‐A (CMGA) and secretogranin‐2 (SCG2), calsyntenin 1 (CSTN1), VGF nerve growth factor inducible (VGF), and phosphatidylethanolamine‐binding protein 1 (PEBP‐1) (Figure S4B ).

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