Barely Significant
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Efficacy and Safety of GLP-1 and Dual GIP/GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension: A Systematic Review and Meta-Analysis.

Eur J Neurol · 2025 · PMC12426903 · PMID 40937960

1
hedged sentence
0.6300
closest p · 12.6× alpha
0.6300
boldest claim

The sentences

did not reach statistical significancep = 0.63not close (p > 0.1)
Regarding visual outcomes, a near‐significant trend toward improved visual acuity with GLP‐1 RA treatment was observed at 3 months (MD = −0.08; 95% CI: −0.17 to 0.01; p = 0.07; 2 studies; I 2 = 0%; p for Cochran's Q = 0.45; Figure 3a ); however, this trend did not reach statistical significance at the end of follow‐up (MD = −0.04; 95% CI: −0.20 to 0.12; 2 studies; p = 0.63; I 2 = 53%; p for Cochran's Q = 0.14; Figure 3b ).

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