Transcriptomic Identification of Immune-Related Hubs as Candidate Predictor Biomarkers of Therapeutic Response in Psoriasis.

Int J Mol Sci · 2025 · PMC12427958 · PMID 40943056

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0690

boldest claim

The sentences

showed a trendp = 0.060so close (0.05 < p ≤ 0.1)

At baseline, patients with severe PASI (>10) showed a trend toward higher expression of CXCL10 ( p = 0.060) and CXCL9 ( p = 0.060) in NL skin compared to those with mild PASI (≤10) ( Figure 2 D).

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a statistical trendp = 0.069so close (0.05 < p ≤ 0.1)

When stratifying the plasma levels of immune-related hubs by previous treatments (topical, biologic, and other), a statistical trend was observed for IL-6 ( p = 0.069) ( Figure 6 E).

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