Effect of High-Fat Diet on Cardiac Metabolites and Implications for Vulnerability to Ischemia and Reperfusion Injury.

EC and phosphorylation potential were not statistically significantly different ( Figure 7 A,C); however, both showed a strong trend ( p < 0.07) for significant differences between groups, which in both cases appears to have been driven by a decrease only in the high-fat group, which is consistent with the decreased ability of the heart to produce energy to improve salvage and sustain function.

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