Combined Hesperidin and Doxorubicin Treatment Induces Apoptosis and Modulates Inflammatory Cytokines in HeLa Cervical Cancer Cells.

Int J Mol Sci · 2025 · PMC12428936 · PMID 40943673

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

The highest caspase-3/7 activity was detected in the combined treatment group (Hes + DX), and this increase was statistically highly significant compared with the control group ( p < 0.001).

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did not reach statistical significanceno p-value reported

At the 48 h time point, Bcl-2 expression was found to be decreased in both the DX and Hes groups compared with control; however, the reduction did not reach statistical significance in the DX group.

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