Shiitake Mushroom-Derived Vesicle-like Nanoparticles Improve Cognitive Function and Reshape Gut Microbiota and Fecal Metabolome in Aged Mice.

Our findings are highly significant considering the lack of effective strategies to combat cognitive decline in clinical settings.

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S-VLN-treated mice tended to have improved glucose homeostasis, but the difference did not reach statistical significance ( Figure 2 G).

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