Identification of <i>TMEM106B</i> as a Shared Potential Drug Target for Depression and Stroke Through Comprehensive Genetic Analyses.

While the MR-Egger estimate did not reach statistical significance, the effect remained directionally consistent across the weighted-median, MR-Egger regression, and MR-PRESSO methods, and was not affected by both correlated and uncorrelated pleiotropy (CAUSE: OR = 1.07, 95% CI = 1.02−1.13, p =7.58 × 10 −3 ) ( Figure 4 ).

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