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Extracellular vesicle-associated transcriptomic and proteomic biomarkers show in vitro potential for vandetanib treatment monitoring in anaplastic thyroid cancer.

Sci Rep · 2025 · PMC12432113 · PMID 40940449

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AHNAK2 was significantly downregulated in the cfRNA at EC80 and GPRC5C showed consistent downregulation across all vandetanib doses in cfRNA compared to DMSO, although this did not reach statistical significance.

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