Barely Significant
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High baseline PD-1+ CD8 T Cells and TIGIT+ CD8 T Cells in circulation associated with response to PD-1 blockade in patients with non-small cell lung cancer.

Cancer Immunol Immunother · 2025 · PMC12433424 · PMID 40944710

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showed a trendno p-value reported
In contrast, the baseline IFNγ expression showed a trend toward being higher in nonresponders compared to responders to PD-1/PD-L1 blockade (Supplementary Fig. 1 C), though the difference was not statistically significant.

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