The effect of neoadjuvant chemotherapy on survival outcomes subsequent to radical cystectomy in pathological T0 bladder cancer patients: A multicenter large-scale analysis.

While other factors such as NAC status, LVI, and clinical staging were not independently associated with OS in the multivariable analysis, age (HR 1.066, p=0.001), pathological N ≥1 (HR 3.276, p=0.077), and tumor grade (HR 0.227, p=0.054) approached significance ( Table 3 ). 3) Cancer-specific survival In the univariable analysis, significant factors were identified as NAC status (HR 0.211, p=0.014), pathological Nx (HR 10.285, p<0.001), pathological N ≥1 (HR 8.188, p=0.001), and LVI (HR 11.491, p=0.019).

also in 8,237 other papers