Causal relationship between multiple sclerosis and asthma and chronic obstructive pulmonary disease based on genome-wide association study data.

Medicine (Baltimore) · 2025 · PMC12440410 · PMID 40958274

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a decreasing trendno p-value reported

MS upregulates TH1, and studies have shown that MS is associated with a decreasing trend in asthma risk mediated by IgE.

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borderline significantno p-value reported

P -values were borderline significant after Bonferroni correction.

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nominally significantno p-value reported

Two-sided P < .05 was nominally significant, P < .025 = 0.05/(1 exposure × 2 outcomes) was Bonferroni significant for main MR analysis.

also in 7,732 other papers

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