Multi-omic spatial profiling reveals the unique SARS-CoV-2 lung microenvironment and collagen VI as a predictive biomarker in severe COVID-19.

Eur Respir J · 2025 · PMC12441580 · PMID 40473310

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Macrophages, neutrophil and T-cells showed a trend towards increasing numbers in late-stage disease cases compared to early-stage, despite clearance of the virus from late-stage cases ( figure 3c , supplementary figure S3 ).

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