A Phase-II Investigator-Initiated Randomized, Double-Blind, Parallel-Group Clinical Trial of 5-Aminolevulinic Acid Hydrochloride/Sodium Ferrous Citrate (5-ALA-HCl/SFC) for Patients With Adult-Onset Still's Disease (AOSD) Refractory to Corticosteroids.

Cureus · 2025 · PMC12441657 · PMID 40970049

Europe PMC DOI

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showed a trendno p-value reported

While the primary endpoint (adapted ACR 30) was achieved in all cases, the high-dose group showed a trend toward efficacy in several secondary endpoints compared with the other groups.

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