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PFKM-Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation.

Adv Sci (Weinh) · 2025 · PMC12442653 · PMID 40569576

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At 3 months of age, the atrial lactate content in the CREM mice showed an upward trend compared to the control group, but it did not reach statistical significance ( Figure 2 A ).

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