Barely Significant
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First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high metastatic colorectal cancer.

Oncologist · 2025 · PMC12445664 · PMID 40833920

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showed a trendno p-value reported
Briefly, patients across all subgroups, except those with lung metastases, showed a trend towards superior PFS and OS with the anti-CTLA-4-based combination.

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