Intravenous Arginine Stimulates Glucagon Secretion More Than Equimolar Alanine, Leucine, Glutamine, and Proline in Humans.

J Endocr Soc · 2025 · PMC12448861 · PMID 40980546

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a nonsignificant trendno p-value reported

Alanine injection resulted in a minor increase in the peak concentration of glucagon, while glutamine showed a nonsignificant trend toward increased glucagon secretion.

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showed a trendno p-value reported

Conversely, proline injection did not stimulate insulin secretion, while leucine showed a trend toward stimulation.

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