Double-Strand Breaks Induce Nuclear-Cytosolic Shuttling of Polymorphic DNA Mismatch Repair Protein MutS Homolog 3 and Binding to NEMO/IKKγ in Colon Cancer Cells.

Within CaCO2 WT/WT cells, all MMR proteins, including WT MSH3, appeared to increase their nuclear amounts (with decreased percentages of cytosolic proteins), although the changes did not reach statistical significance ( Figure 6 B).

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