Belantamab Mafodotin with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: A Comprehensive Exposure-Response Analysis of the DREAMM-8 Study.

There was a slight trend of decreasing probability as cys-mcMMAF exposures increased, but this did not meet significance criteria, nor did any covariate association.

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While logistic regression showed patients with these events had slightly higher belantamab mafodotin exposures, and there was a small trend for decreasing probability of event with increasing cys-mcMMAF exposures, neither exposure metric was significant.

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Similarly, Kaplan–Meier analysis showed a trend for earlier grade ≥ 3 corneal exam findings with higher belantamab mafodotin exposures, but stepwise Cox regression found no significant associations with time to these exam findings.

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