Benzo[a]pyrene and UV light co-exposure: differential effects on oxidative stress and genotoxicity in human keratinocytes and ex vivo skin.

Arch Toxicol · 2025 · PMC12454581 · PMID 40593241

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While combined B[a]P and UV treatment showed a trend towards increased B[a]P uptake compared to single exposure, the effects on 3-OH B[a]P and B[a]P-tetrol formation differed. 3-OH B[a]P levels were notably elevated, whereas B[a]P-tetrol levels increased only modestly, despite statistical significance.

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