Barely Significant
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Carbon-Ion Radiation Therapy Compared to Surgical Resection for Primary, Solitary, Potentially Resectable Hepatocellular Carcinoma.

JGH Open · 2025 · PMC12455018 · PMID 40995609

1
hedged sentence
0.0880
closest p · 1.8× alpha
0.0880
boldest claim

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did not reach statistical significancep = 0.088so close (0.05 < p ≤ 0.1)
Upon multivariate analysis (Table 2 ), which includes the treatment procedure, age, AFP level, tumor size, and ALBI grade, tumor size was the factor most likely associated with OS; however, it did not reach statistical significance (HR 6.006; p = 0.088). 4.3 Local‐Control Rate Figure 3 illustrates the cumulative local‐control rates after CIRT and LR in the overall cohort.

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