Serum metabolomics reveals one-carbon metabolism differences between lean and obese cats not affected by L-carnitine or choline supplementation.

The significance of the lower concentrations of C8 and C12 with choline treatment in relation to FA oxidation is unclear, as the total concentration of medium-chain acylcarnitines tended to differ with treatment but did not reach statistical significance. mApart from the effects of dietary treatment in the present study, lean and obese cats had differences in their serum metabolomic profiles, specifically in relation to one-carbon metabolism ( Figure 3 ).

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