Efficacy and Safety of Lorundrostat in Uncontrolled Hypertension: A Systematic Review and Meta-Analysis.

J Clin Hypertens (Greenwich) · 2025 · PMC12459306 · PMID 40991241

Europe PMC DOI

hedged sentence

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

did not reach statistical significancep = 0.077so close (0.05 < p ≤ 0.1)

Lorundrostat reduced office SBP compared to control; however, this did not reach statistical significance (MD −13.55 mmHg, 95% CI: −28.57 to 1.47; p = 0.077) (Figure 2 ).

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