Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8<sup>+</sup> T cells.

Brain Commun · 2025 · PMC12459988 · PMID 41000171

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did not reach statistical significanceno p-value reported

13 , 14 In Tau Tg mice, FTY720 treatment also led to a reduction in lymphocytes, although the decrease in B cells did not reach statistical significance ( Fig. 1B–G ).

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Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8&lt;sup&gt;+&lt;/sup&gt; T cells.

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Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8<sup>+</sup> T cells.