Distinct effects of semaglutide and tirzepatide on metabolic and inflammatory gene expression in brown adipose tissue of mice fed a high-fat, high-fructose diet.

Furthermore, tirzepatide administration resulted in a lower AUC value (1,132 ± 115.7 mmol/L × min) than semaglutide (1,492 ± 113.2 mmol/L × min), though the difference did not reach statistical significance. 3.3.

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