Barely Significant
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Cardioprotective effectiveness of SGLT2 inhibitors in older diabetic women with early-stage breast cancer following anthracycline- and/or trastuzumab-based treatment.

Ther Adv Med Oncol · 2025 · PMC12461033 · PMID 41018041

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Although there was a tendency toward lower point estimates for the cardiovascular composite endpoint and incident HF or CM in the SGLT2i group compared to the OAM group, the differences in the risk for all CV outcomes did not reach statistical significance ( Supplemental Tables 3 and 4 ).

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a nonsignificant trendno p-value reported
Consistent with findings from the ITT analysis, a nonsignificant trend toward a reduced risk estimate was observed for the composite CVD and new HF or CM diagnosis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.