Sustained frailty remission and future cardiovascular disease risk: a longitudinal study from the UK Biobank.

Arch Public Health · 2025 · PMC12462044 · PMID 40993761

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did not reach statistical significanceno p-value reported

Importantly, formal tests for interaction between frailty transition patterns and age or sex did not reach statistical significance ( P for interaction > 0.05), suggesting that these observed subgroup differences may represent trends rather than true effect modification.

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marginally nonsignificantno p-value reported

Among females, sustained remission was significantly associated with a lower risk of incident CVD in the unadjusted model (HR = 0.57, 95% CI: 0.37–0.90) and remained protective though marginally nonsignificant after adjusting for confounders (HR = 0.64, 95% CI: 0.38–1.08).

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