Although there was a trend toward lower all-cause mortality, it did not reach statistical significance (HR: 0.70; 95% CI: 0.46 to 1.08; P 1⁄4.09). 27 The most common adverse event associated with nintedanib is diarrhea (62.4%), which is manageable by symptomatic treatment and can be resolved without the need for dose reduction or interruption of treatment.
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Antifibrotic therapies in rheumatoid arthritis associated interstitial lung disease.
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