In contrast, the expression of the M2 marker CD206 was only slightly reduced and did not reach statistical significance, supporting a specific role of endothelial APP in promoting M1 polarization of macrophages (Figure S7A , Supporting Information).
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CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression.
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