Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain.

Elife · 2025 · PMC12463392 · PMID 40996791

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did not reach statistical significanceno p-value reported

The comparative analysis of the sum expression of UIDs per individual comparing young (≤65 y) with elderly human dopaminergic neurons, however, did not reach statistical significance ( Figure 5C ).

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