Cellular and proteomic differences associated with lithium response in olfactory neuroepithelium cells of bipolar disorder patients.

Mol Med · 2025 · PMC12465717 · PMID 41013196

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highly significantno p-value reported

This analysis revealed several highly significant biological processes and pathways, consistently appearing across multiple group comparisons.

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did not reach statistical significanceno p-value reported

This finding suggests that distinct proteins related to cell migration may underlie the observed effects in BDR cells compared to BDNR, as indicated by proteomic analyses of “Cellular Movement.” Although lithium treatment tended to enhance migration in BDR cells, this effect did not reach statistical significance.

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