Sex-Specific Association Between XPC rs2228001 Polymorphism and Parkinson's Disease Risk in a Mexican Population: A Case-Control Study Exploring Gene-Environment Interactions.

Brain Sci · 2025 · PMC12468217 · PMID 41008368

Europe PMC DOI

hedged sentence

0.0870

closest p · 1.7× alpha

0.0870

boldest claim

The sentences

did not reach statistical significancep = 0.087so close (0.05 < p ≤ 0.1)

Although individuals homozygous for the C allele (C/C genotype) showed a higher risk of PD after adjusting for pesticide exposure and cognitive status (MMSE score), the association did not reach statistical significance (OR 2.35, 95% CI 1.08–5.11; p = 0.087; Table 4 ).

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