Artificial Intelligence-Enhanced Precision Medicine Reveals Prognostic Impact of TGF-Beta Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer Among Disproportionately Affected Populations.

Int J Mol Sci · 2025 · PMC12469963 · PMID 41009631

Europe PMC DOI

hedged sentence

0.0541

closest p · 1.1× alpha

0.0541

boldest claim

The sentences

did not reach statistical significancep = 0.0541so close (0.05 < p ≤ 0.1)

Among early-onset cases, FOLFOX-treated patients had a slightly higher median diagnosis age (42 years; IQR 36–47) than those not treated (40 years; IQR 34–43), a difference that approached but did not reach statistical significance ( p = 0.0541).

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