Barely Significant
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ACE-Dependent Alzheimer's Disease: Circulating ACE Phenotypes in Heterozygous Carriers of Rare <i>ACE</i> Variants.

Int J Mol Sci · 2025 · PMC12471119 · PMID 41009662

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quite significantno p-value reported
The frequency of these ACE LoF mutations in the general population is quite significant, up to 5% [ 7 ], which is comparable to the AD frequency in the elderly (>75 y.o.).

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