Investigation of Intestinal Microbiota and Short-Chain Fatty Acids in Colorectal Cancer and Detection of Biomarkers.

Pathogens · 2025 · PMC12472356 · PMID 41011853

Europe PMC DOI

hedged sentences

0.1280

closest p · 2.6× alpha

0.1280

boldest claim

The sentences

did not reach statistical significancep = 0.128not close (p > 0.1)

When fecal short-chain fatty acids were examined in the study groups, acetate, propionate, and butyrate were found to be decreased in CRC patients, although these changes did not reach statistical significance ( p = 0.128, p = 0.086, p = 0.423, respectively) ( Table 5 ). 4.

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a decreasing trendno p-value reported

In addition, serum zonulin levels were significantly elevated, and although not statistically significant, SCFA levels showed a decreasing trend in CRC patients.

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